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Strength Training Is Not Optional Enter strength training, your new best friend if youre on a GLP-1 drug
these changes do not make it a growth-hormone secretagogue, instead they sharply reduce its binding to IGF-binding proteins (IGFBPs), which is what extends its circulating half-life and potency relative to native IGF-1
Think of NNMT as a regulator for your fat cells energy use
Recently, the GIP/GLP-1R co-agonist tirzepatide has gone through several randomized controlled trials and was approved by the FDA for T2DM and obesity in 2022 and 2023, respectively
[1] [3] According to the UK SmPC, dosing starts at 2.5 mg once weekly for 4 weeks, then increases in 2.5 mg increments every 4 weeks until the target dose (5 mg, 7.5 mg, 10 mg, 12.5 mg or 15 mg) is reached, based on individual response and tolerability
Signs to watch for include: Skin rash or hives Itching Swelling of the face, tongue, or throat Difficulty breathing If you experience any of these symptoms, stop the supplement immediately and consult a doctor
