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Apridonidze T, Essah PA, Iuorno MJ, Nestler JE (2005) Prevalence and characteristics of the metabolic syndrome in women with polycystic ovary syndrome

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Modifiable risk factors include cigarette smoking (the strongest modifiable risk factor, with smoking cessation strongly recommended), hypertension, cardiovascular disease, and potentially obesity

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GLP-1s also inhibit the pancreatic alpha cells (-cells) from releasing the hormone glucagon, which typically raises blood sugar by signaling the liver to produce more glucose