These neuroprotective effects appear mediated through enhanced cellular autophagy via TFEB nuclear translocation (Lai et al., 2022)
Crack PJ, Cimdins K, Ali U, Hertzog PJ, Iannello RC
Mechanistically, this system rapidly chelates intracellular Ca, alleviating endoplasmic reticulum stress-related signaling axes (such as ATF4-CHOP), while reducing oxidative damage and apoptosis
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Suwannasom, N., Kao, I., Pru, A., Georgieva, R