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It has been proposed that cytokines (e.g

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In line with this assumption, for all three viruses, we observed a highly significant enrichment of known physical interaction partners of the viral proteome among predicted tier-1 targets compared to tier-2 targets and all other enzymes (Fig

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6.4 Immunomodulatory therapies Immunomodulation has emerged as a promising investigational approach in PD, supported by evidence that microglial activation, inflammasome signaling, and peripheral immune dysregulation may contribute to neurodegenerative processes