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However, a warning from some research reports and National Authorities raised NSAIDs safety concerns because of the supposed induction of angiotensin-converting enzyme 2 (ACE2) levels (the receptor used by SARS-CoV2 to enter host airways cells), the increased risk of bacterial superinfections and masking of disease symptoms

A thorough medical evaluation and baseline inflammatory biomarkers can help contextualize individual risk

The increasing number of affected individuals and families places a heavy burden on the healthcare system(Candon et al., 2018

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