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The rising trend of buccal fat removal helps chisel the cheeks and jaw, but can leave patients looking gaunt before their time

Sheehan D et al

[5] Studies of GHS-R1a signaling in pituitary cells show that receptor activation can involve phospholipase C, adenylate cyclase/protein kinase A, changes in intracellular calcium, and L-type voltage-sensitive calcium channels

This is great for people trying to lose weight, but eating in deficit without controlling for a few different variables can produce adverse health effects as well

However, it appears to be a relatively uncommon side effect

How does semaglutide reduce belly fat