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Peer review Peer review information Communications Biology thanks the anonymous reviewers for their contribution to the peer review of this work

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Lin, S., Deng, Y., Huang, J., et al

Scleroderma affects the skin and other structures, causing the formation of scar tissue

[5] While copper can potentially cause skin irritation or toxicity, in vitro studies suggest that GHK-Cu complexes may have a lower likelihood of inducing these effects