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One way, two way or repeated ANOVA and appropriate post-hoc tests were used to identify significant differences, with a significance level set at p 0.9999)

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Pramlintide, the first generation (1990s) In the 1990s, the pharmaceutical company Amylin Pharmaceuticals developed Pramlintide , a modified amylin with three proline substitutions at positions 25, 28 and 29

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