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Obesity and weight gain following a breast cancer diagnosis are well-established risk factors for increased breast cancer-specific and all-cause mortality

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LPL contains heparin-binding domains that interact with heparan sulfate proteoglycans (HSPGs) and contains lipidbinding sequences that bind TRLs, which bridges capillary HSPGs and circulating TRLs (in a stable multimolecular structure) along the capillary endothelium through the margination process [39]

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