What actually matters more than which site you pick is that you dont pick the same exact spot every single time
Moreover, metformin can directly protect endothelial cells from injury, which is beyond its glucose-lowering effects 7,8
10.1016/j.lfs.2014.09.028 40
In proof-of-concept studies, NNMT inhibitors (NNMTis) have demonstrated promise as potential treatments for obesity and obesity-related metabolic comorbidities (e.g., T2D, fatty liver) 8,9,13
4.1 Future clinical and research applications 4.1.1 Future research directions While reassuring data are accumulating about the safety profile of GLP-1 receptor agonists (GLP-1 RAs) used for diabetes and obesity management, there are still significant gaps in our understanding that justifies the need for well-designed multidisciplinary translational and clinical studies
Abstract Background Obesity in patients with IBD is increasing, accompanied by an increase in metabolic comorbidities