NAA exerts its function in a histone acetyltransferase P300/CBP-associated factor (PCAF)-dependent manner, leading to lamin A acetylation, impairing its interaction with Sun2 (Sad1 and Unc84 domain-containing protein 2) and subsequent lytic granules, from CD8 + T cells and NK cells, polarization and release [214]
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However, it is important to note that it can cause certain side effects, such as dizziness, nausea, headache, and an increase in blood pressure
The plan, which has been working to manage a large shortfall amid rising healthcare costs, still covers the drug as a treatment for diabetes
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Invest Ophthalmol Vis Sci 56(12):73037311 Singh S, Singh S, Kumar A (2022) Systemic Candida albicans infection in mice causes endogenous endophthalmitis via breaching the outer blood-retinal barrier