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This mutant can still synthesize glutathione, but is not able to produce the inner membrane ABC-transporter CydDC that transports glutathione from the cytosol into the periplasm and hence suffers from reduced periplasmic glutathione levels (Mironov et al., 2020
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Excess dietary L-cysteine, but not L-cystine, is lethal for chicks but not for rats or pigs
These observations were reaffirmed by Zare and co-workers who used the same doses (0.3 and 0.6 mg/mL) of LC supplementation during in vitro maturation of immature BCB+ (Brilliant Cresyl Blue positive) oocytes
Additionally, aging and certain skin conditions may impair the skins barrier function, making it harder to retain moisture
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