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This is likely explained by our previous finding that, compared with normal tilapia, CPT1 is overexpressed in MD-treated tilapia as a compensatory response to carnitine deficiency and the associated low -oxidation capacity ( Reference Pan, Li and Li 34 )

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12 Unfortunately, best results require combining a considerable (~80 grams) load of carbohydrates to push the L-carnitine into the skeletal muscle and increase muscle stores, as well as increasing energy expenditure