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IL-17A, as the major inflammatory mediator (37), increases bone resorption during RA

Patients with sleep apnea, high blood pressure, or certain optic nerve anatomy may face higher risk

A 2022 cohort study of over 106,000 patients found an increased risk of acute liver injury in women taking GLP-1 agonists compared to other diabetes drugs

PMID 11353742

Semaglutide prescriptions for weight loss have surged over the past three years, with clinical trials showing average weight loss between 1022% of body weight depending on dosing and duration