For example, following the induction of intestinal ischemia in humans, a rapid increase in GLP-1 secretion was observed, suggesting a link between endogenous LPS translocation and GLP-1 activation under conditions of barrier dysfunction (Lebrun et al., 2017)
J Thorac Oncol 3(9):979-84, 2008
The role of GLP-1R in type 2 diabetes mellitus (T2DM) is highlighted, emphasizing its pivotal contribution to glucose homeostasis, promoting -cell proliferation, and facilitating insulin release
Indeed, GLP-1 agonists appear to be helpful for gastrointestinal diseases such as IBS, ulcerative colitis, and Crohns disease
was supported by Takeda Science Foundation 2019 Medical Research Grant and Japan Science and Technology Agency PRESTO (18069571)
Evaluating the Effects of the Novel GLP-1 Analogue Liraglutide in Alzheimers Disease: Study Protocol for a Randomised Controlled Trial (ELAD Study). Trials, vol