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Its emergence reshaped the field's expectations for incretin-based compounds and laid the conceptual foundation for the subsequent triple-agonist class exemplified by retatrutide

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First-quarter revenue rose 56% to $19.8 billion on a 65% jump in volume, with Mounjaro and Zepbound supplying roughly $12.8 billion between them, and full-year guidance climbed to $82-85 billion

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