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Intestinal epithelial sirtuin 1 regulates intestinal inflammation during aging in mice by altering the intestinal microbiota

Weekly GLP-1 medications build steady-state blood levels over 4 to 5 weeks of consistent dosing

One key study cited that 1.5% of users taking 0.5 mg doses of Ozempic developed gallstones, while another study showed a risk of up to 1.27 times higher for gallbladder conditions when using glucagon-like peptide-1 receptor agonists (GLP-1 RAs), the class of drugs to which Ozempic belongs

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The switch requires a new consultation ($75) and adjusted dosing