Derived from the proglucagon gene, oxyntomodulin acts as a dual agonist at GLP-1 and glucagon receptors, promoting satiety and increasing energy expenditure (Cohen et al., 2003)
Funding This work was supported by the Ministry of Science and Technology of China, the National Key Research and Development Program of China (2022YFF1100205)
Does this mean that we have to resign ourselves to treating obesity for life, a bit like controlling hypertension, excess blood cholesterol or even insulin deficiency, with the help of drugs that should be administered continuously from the onset of pathologies
By reducing appetite and supporting sustained weight loss, GLP-1 therapy can improve insulin sensitivity over time
PMID: 9533463 Quillot D, Walters E, Bonte J-P, Fruchart J-C, Duriez P, Ziegler O
We recognize the connection between mental well-being and weight management