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In addition, pericyte- and astrocyte-mediated angiopoietin-1/Tie2 signaling maintains endothelial junctional equilibrium and counterbalances angiopoietin-2-driven vascular leakage, thereby strengthening the barrier within the CNS endothelium [236]
Pathogen blockade of TAK1 triggers caspase-8-dependent cleavage of gasdermin D and cell death
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