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2 Thus, there is a tremendous amount of research under way to further elucidate these mechanisms and, more important, to discover pharmacologically based strategies that correct these separate, but intertwined, physiologic derangements
However, any rectal bleeding warrants prompt medical assessment to identify the underlying cause, which may include haemorrhoids, inflammatory bowel disease, or more serious conditions
Encyclopedia of Food and Health (Elsevier, 2016)