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In this experiment, calibrated Von Frey filaments were employed to evaluate joint pain sensitivity as previously described 38,39 , the results showed that metformin treatment increased the paw withdrawal thresholds compared with those in MIA-induced OA model group (Fig

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For echoviruses, several studies have shown either an interaction with FcRn or a FcRn-dependency in infectious ability for at least seven distinct serotypes, indicating that FcRn is likely targeted by a broad range, if not all, echoviruses [376, 378]

4,5 Though clomiphene citrate is typically well tolerated, it can be associated with adverse effects including hot flashes, headache, or gynecomastia among others

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pH-sensitive amphiphilic chitosan-quercetin conjugate for intracellular delivery of doxorubicin enhancement