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Personalized evaluation helps ensure that recommendations are aligned with each individuals needs

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In white adipose tissue, blocking NNMT elevated resting calorie burn, decreased adiposity, and improved insulin sensitivity in rodent models, independent of diet or activity changes (Kraus et al., Nature Medicine )

Along with vitamin C, vitamin B12 might interact with other substances

There are also cardiovascular benefits: B12 helps process the amino acid homocysteine, which when elevated can contribute to things such as stroke