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Embodiment 34 The process according to Embodiment 29, wherein the second RP-HPLC purification uses a mobile phase C comprising an ammonium salt or a phosphate salt and a mobile phase D comprising acetonitrile

No adjustments were made for multiple comparisons.P values for interaction were calculated using multiplicative interaction terms

These symptoms can even appear even before a full-blown deficiency develops ( While fatigue and irritability may be some of the first symptoms to appear, they typically resolve after just a few days of adequate intake or within 24 hours of high-dose supplementation ( Summary Signs of fatigue and poor mood can appear even with low-to-normal levels of vitamin C, but they quickly turn around with adequate vitamin C intake

These are molecular observations in experimental systems not human outcomes and not guidance for use

Eur J Rheumatol 4(1):4656

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