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Transcriptomic analysis was conducted on liver tissues from Gipr fl/fl , Gipr Syn / , Glp1r fl/fl and Glp1r Wnt1 / mice treated with either vehicle or mGIPR-Ab/P1

The p27 protein can inhibit the transduction of the rho-associated kinase (RhoA) signaling pathway, consequently reducing the migratory and invasive capacity of tumor cells [76]

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Because of this shift, evaluating the long-term safety profile of GLP-1 therapies has become increasingly important