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GLP-1 signals to the brain that the stomach is full, stimulates the pancreas to produce insulin in response to meals, and slows gastric emptying (food leaves the stomach more slowly, extending the feeling of fullness)

Rapamycin-induced autophagy ameliorates GSH depletion-induced premature cell senescence It was shown that autophagy activation especially in the presence of an increasing autophagic flux inhibits the senescence of RPE cells 35,36,37,38,39

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The injectable version doesnt have these issues and gives more consistent results

10.1016/j.cbi.2008.10.052 Chem