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Yes, definitely
As with other agents that cause significant weight loss or gastrointestinal fluid losses, there are theoretical class-related risks that warrant attention, including gallbladder disease (cholelithiasis and cholecystitis have been reported with GLP-1 receptor agonists), and dehydration or acute kidney injury in the context of persistent vomiting or diarrhoea
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Where Kickoff Excels Supportive communication, lower intimidation, simple guidance, and an accessible entry point for newer exercisers
This raises questions about their quality, consistency, and long-term safety
I am going to focus on three: the SGLT2 inhibitors, pioglitazone and GLP-1 receptor agonists
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