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Avoid smoking and alcohol, which accelerate collagen degradation and inhibit repair

Summary of preclinical and clinical evidence for the anti-fibrotic potential of incretin agonists across organ systems

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A Novo Nordisk study included 2,000 participants with obesity or overweight and a weight-related health condition (excluding type 2 diabetes) who were given a 2.4 mg dose of semaglutide for 68 weeks

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Osteoarthritis patients exhibited a lower relative abundance of Clostridium bolteae , which promoted the formation of ursodeoxycholic acid (UDCA), a precursor of GUDCA