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This was followed by the titration of carbonyl cyanide-p-tri-fluoromethoxyphenylhydrazone (FCCP) to induce maximal capacity of the electron transport system (ETS) in the uncoupled state, labeled ET capacity (alternatively known as NS-ET capacity)

However, in GCLM KO mice, genes encoding lipid synthesis enzymes, Fasn and Scd , were further down-regulated, whereas Fads1 was up-regulated by ethanol, the net effect of which would be expected to result in lower levels of total TG and increases in the relative abundance of certain lipid species

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These actions contribute to improved cognitive function, reduced disease progression, and enhanced brain health