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Description

Eli Lilly developed tirzepatide based on the observation that GIP and GLP-1 produce complementary metabolic effects

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Ang J-J, Low B-S, Wong P-F (2024) Dopamine and central dopaminergic circuitry in neurodegenerative diseases: roles and mechanisms of action of natural phytochemicals

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Dopamine is involved in motivation and reward circuits, and lower D2 receptor levels may lead to reduced activation of these circuits

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