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Melanotan 1, also known by its research name Afamelanotide, is a synthetic analog of a naturally occurring peptide hormone called alpha-melanocyte-stimulating hormone (-MSH)
10.1067/j.cpradiol.2011.01.003 9
The brand is FDA Approved- (FDA FR- 4000001507203) and produced in compliance with the latest FDA cGMP Standards in the US
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In vitro studies have examined its interaction with endothelial cell migration, fibroblast proliferation, and nitric oxide synthase (NOS) system modulation, documenting activation of the VEGFR2-Akt-eNOS and Src-Caveolin-1-eNOS signalling axes in vascular endothelial cells [1]
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