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Studies conducted with Caco-2 cells in a laboratory setting, utilizing inhibitors of transporter proteins and knockout methods, have pinpointed the main transporter proteins responsible for metformin as the organic cation transporters (OCTs), plasma membrane monoamine transporter (PMAT), serotonin transporter (SERT), and high-affinity choline transporter (CHT) (Han et al., 2015)
Because peptides can target specific tissues or pathways, they offer a more precise approach than broad treatments like steroids or NSAIDs
A few noted they pair it with sunscreen or vitamin C for better results
May 27, 2021
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