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Participants randomized to orforglipron increased the dose every 4 weeks until reaching 36 mg or MTD

SURMOUNT-3 and SURMOUNT-4: These later trials looked at how the medication worked when combined with intensive lifestyle interventions and how patients maintained their progress over time

Many individuals notice a more even skin tone, a refreshed complexion, and an overall healthier glow over time

However, injections are not the only way to achieve high bioavailability

Sherly Soleiman, MD discusses both options with patients and selects the appropriate formulation based on clinical fit, supply, and individual needs

DXA scans followed 155 participants at baseline, with 103 completing both baseline and week 36 scans, to monitor changes in muscle and fat