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Instead of beginning at the conventional 0.25 mg weekly or a full pen dose, microdosing might start at a fraction a fifth to a tenth and slowly increase

It is generally recommended to avoid excessive alcohol consumption while taking GLP-1s

Reference: DAnnibale DA et al

This action is thought to subsequently elevate levels of insulin-like growth factor-1 (IGF-1), which is viewed as the primary agent responsible for the anabolic action of growth hormone

Since the U.S

Standard practice includes: Baseline thyroid function tests (TSH and free T4) before initiating GLP-1 therapy Repeat testing at 812 weeks after starting treatment or after dose escalation Regular monitoring every 36 months during active weight loss Return to annual monitoring once weight is stable and thyroid function remains consistent Adjustments to levothyroxine dosing may be necessary as weight changes