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Based on the well-established PERK signaling pathway [148151], we hypothesize that TMAO binds to PERK, triggering its dimerization and autophosphorylation, thereby activating it (Figure 2)

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GLP-1 stands for glucagon-like peptide-1:a hormone your intestine naturally produces after eating

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Statements Author contributions LF: Writing original draft

Lumbar spine support diminishes with decreased core muscle mass and endurance