Kokura Y et al
doi: 10.1007/s12020-021-02730-0 Summary Keywords growth hormone, insulin-like growth factor, GLP-1RAs, SGLT-2is, diabetes Citation Cignarelli A, Genchi VA, Le Grazie G, Caruso I, Marrano N, Biondi G, DOria R, Sorice GP, Natalicchio A, Perrini S, Laviola L and Giorgino F (2022) Mini Review: Effect of GLP-1 Receptor Agonists and SGLT-2 Inhibitors on the Growth Hormone/IGF Axis
As noted by the FSBP CEO Kyle Longton , there is a high discontinuation count for GLP1s, this is one of the primary reasons
Staying well-hydrated is not optional on this combination
Sustains energy levels*
Your provider may check your hemoglobin A1c to assess diabetes control, review your medication regimen for potential contributors (particularly SGLT2 inhibitors), and consider whether treatment adjustments are needed