Glucagon-like peptide-1 (GLP-1) receptor agonists, including semaglutide (Ozempic, Wegovy), dulaglutide (Trulicity), and liraglutide (Victoza, Saxenda), have become widely prescribed for type 2 diabetes management and weight loss
Furthermore, 43% of these firms with 1,000 to 4,999 workers, and 66% of these firms with 5,000 or more workers said that covering GLP-1s for weight loss had a significant impact on their plans prescription drug spending
This approach has been successfully applied in IMMU-110, which contains a cleavable acyl hydrazone linker formed by reaction between the hydrazide of 4-maleimidomethyl cyclohexane-1-carboxylate (MCC) and the keto group of doxorubicin
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