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In certain clinical trials, when compared to a placebo, patients who used Wegovy lost about 15% of their starting body weight in the first 1 to 1.5 years, Zepbound medication users lost 16%, Foundayo medication users lost 12.4%, and Saxenda users lost 5%
Nonetheless, these clinical trials were underpowered to detect rare events such as suicidal ideation and self-injurious behavior, and they systematically excluded patients with psychiatric comorbidities commonly seen in clinical settings
Neuropharmacology 62 , 19161927, (2012)
