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MitoQ intervention inhibits nitrotyrosine concentration and improves mitochondrial and endothelial functions (Braakhuis et al., 2018)

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Once the maintenance dose is reached, however, the effect generally stabilizes

These complications could prove fatal without urgent medical attention

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Overall, considering the evidence reported here, the cellular antioxidant defense in ALS appears to be strongly diminished, with an imbalance towards high and persistent OS levels