Y250 is located much farther from the disulfide bonds (Cys128-Cys206 in the hinge region between K1 and K2 domains, and Cys211-Cys288, Cys232-Cys271, and Cys260-Cys283 in the K2 domain) than the distances between Y198 and disulfide bonds, Cys149-Cys189 and Cys177-Cys201
Two major B12-dependent pathways matter most for neuropathy
J Rheumatol 1984;11:211-2
Readers should treat every comparison below as indirect evidence, not proof of superiority
Unlike most signalling peptides in the research literature, BPC-157 does not target a single well-characterised receptor
As an additional control, growth inhibition assays were conducted on the antimalaria compounds artemisinin and chloroquine: the IC 50 values obtained (12 nM and 22 nM, respectively) are comparable to previously published results ( Supplementary Figure 6 )