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The Phase 3 TRIUMPH-4 trial pushed these numbers even higher, with the 12 mg dose achieving 28.7% mean weight loss at 68 weeks

Any consideration of GLP-1 therapy should involve comprehensive evaluation by an endocrinologist or appropriate specialist, with clear discussion of the investigational nature of this approach, potential risks, costs, and the importance of ongoing monitoring

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At the same time, it reduces the release of glucagon, another hormone involved in raising blood sugar

PT-141 may be considered for certain adults who: Have concerns related to low sexual desire Are interested in discussing non-hormonal treatment options with a licensed provider Want a provider-guided evaluation to determine whether treatment is appropriate Treatment decisions should be based on an individual medical review, including symptoms, health history, and treatment goals