Wang J, Wang PM, Gu Y, Kopittke PM, Zhao FJ, Wang P
Despite reports of melanoma, according to a study of social media posts the drug is often marketed as protecting against skin cancer
The mechanism involves gene regulation in chondrocytes (cartilage cells) - Cartalax binds to specific DNA sequences in cartilage tissue, upregulating genes for cartilage matrix proteins (collagen type II, proteoglycans, aggrecan), downregulating inflammatory and degradative enzymes (matrix metalloproteinases), and optimizing the balance between cartilage formation and breakdown
DOI: 10.1126/science.2578228 34
Following the animal study, the researchers conducted a proof-of-concept human study (N=87) with hepatic steatosis using only serine
Owing to the complexity of ferroptosis and the lack of specific criteria and unique biomarkers of ferroptosis, we were unable to conclude that ferroptosis is involved in the mechanism of EBV reactivation