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BraigDKaiserBThieleJRBannaschHPeterKStarkGBet alA conformational change of C-reactive protein in burn wounds unmasks its proinflammatory properties

Chim Oggi/chem Today 28:1416 Mohapatra A, Rajendrakumar SK, Cherukula K, Park MS, Padmanaban S, Vasukuty A, Mohanty A, Lee JY, Bae WK et al (2023) A sugar modified amphiphilic cationic nano-adjuvant ceased tumor immune suppression and rejuvenated peptide vaccine induced antitumor immunity in cervical cancer

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TB-500s key mechanisms include: Actin sequestration: By binding G-actin (monomeric actin), TB-500 keeps it available for cell migration and wound repair rather than polymerizing prematurely into structural filaments