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Su caracterstica diferenciadora dentro de la clase es estructural: una acilacin con un espaciador y una cadena grasa C18 en la posicin 26, combinada con una sustitucin del aminocido en posicin 34 (lisina por arginina), que alarga su semivida hasta aproximadamente 165 horas y permite la administracin semanal por va subcutnea o diaria por va oral

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