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Daily injections of 12mg for rapid correction of significant deficiency, then weekly maintenance

once the compound clears, NNMT resumes normal activity

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severe thiamine deficiency, while rare, can cause Wernickes encephalopathy in hyperemesis gravidarum, and inadequate B is associated with anemia and neurologic issues in the newborn

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Sleep apnea The SURMOUNT-OSA trial demonstrated that tirzepatide reduced the severity of obstructive sleep apnea significantly, with some patients achieving complete resolution