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Sin embargo, ms all de la eficacia para el control metablico, los lineamientos actuales en la terapia farmacolgica de la diabetes mellitus se dirigen hacia la proteccin en el mbito cardiovascular y sus complicaciones, por lo que este grupo farmacolgico se posiciona como una opcin importante al demostrar reduccin de los eventos cardiovasculares comparados con placebo que podran ser equiparables a los presentados recientemente por los inhibidores del SGLT-2

10.4093/dmj.2019.0185 66 GreenH.TsitsiP.MarkakiI.AarslandD.SvenningssonP

35,36 Although some studies report smaller reductions in muscle mass, many scientists argue that these findings should not be ignored due to the high metabolic rate of skeletal muscle which plays an important role in maintaining significant weight loss

doi: 10.3945/jn.109.104638, 131

Pain that doesnt feel like typical [gastrointestinal] upset and is disproportionate to meals or exercise should be taken really seriously. Hector Perez, MD Ali said that patients should receive all necessary information about potential side effects before starting the medication

Always consult with your physician or other qualified health care provider before embarking on a new health regimen, diet or fitness program