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Early research results on bone health and the use of GLP-1s are mixed, with some randomized trials and meta-analyses suggesting neutral or modestly protective effects on bone density and fracture risk

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Risks associated with corticosteroid medication include high blood pressure, high blood sugar, poor growth, or cataracts

PMID 11707452

NF-kappa B regulates IL-1 beta transcription through a consensus NF-kappa B binding site and a nonconsensus CRE-like site