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Name: surmount-1 trial tirzepatide weight loss nondiabetic SURMOUNT‐1 study design. This is a phase 3, multicenter, randomized, surmount-1 trial tirzepatide obesity without
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TZP demonstrates robust protective effects on the BBB in ischemic stroke models

\Withdrawal Management: 97% success in opioid withdrawal

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The pattern of AEs reported within different system organ classes and preferred terms was also comparable between treatments

504 Increased number of GFAP-positive astrocytes, oligodendrocytes and microglia were detected in the striatum, with no changes in glial numbers in the amygdala