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The most promising compounds, 39 and 40 (Figure 6), showed an IC 50 of 2.80 nM against DPP-4 catalytic activity, with 20 - 40-fold selectivity over the DPP-8 and DPP-9 isozymes

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280,281 11 Nutrients Omega-3 Fatty Acids The long-chain polyunsaturated omega-3 fatty acids, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), are important components of nerve cell membranes, affecting their fluidity and ability to send and receive signals

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Next, the cells were digested with pancreatic enzyme without EDTA for 1 ~ 2 min and collected in the corresponding centrifuge tubes by a centrifugation (1000 rpm, 5 min)

Purification of proteins fused to glutathione S-transferase