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Preclinical studies indicate that NNMT knockdown or inhibition can protect against diet-induced weight gain and improve metabolic parameters without reducing food intake [8] [9]

We found that Mia40 existed as a mixture of oxidized and reduced molecules contrary to most invitro studies that found Mia40 mainly in the oxidized state (Mesecke et al , 2005

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Structural investigations of full-length insulin receptor dynamics and signalling

Low zinc, poor ceruloplasmin production or impaired biliary copper excretion may worsen copper-related oxidative stress