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doi:10.1080/10408363.2021.1885339
Neuroprotective effects of vitexin, a flavonoid, on pentylenetetrazoleinduced seizure in rats
Subsequently, unique gene hit counts were calculated using featureCounts from the Subread package v.1.5.2 by summarizing and reporting the hit counts based on the gene id feature in the annotation file 26
Concurrently, there was a significant upregulation in Lamp1 and Lamp2 (Proteins involved in the regulation of lysosomal pH) [58], lysosomal acidic hydrolases, and metabolites such as PE and M6P (a signalling molecule for the transportation of newly synthesised lysosomal enzymes to lysosomes) [59], while Sqstm1 protein levels were notably downregulated
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